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SMILES: CC(=O)N1Cc2cc(Br)ccc2N(Cc2cnc[nH]2)CC1Cc1ccccc1

InChI Key: InChIKey=MESCZZRDZFQCFT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092362   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dimer of Protein farnesyltransferase subunit beta


(Homo sapiens (Human))		BDBM50092362
PNG
(1-[3-Benzyl-7-bromo-1-(3H-imidazol-4-ylmethyl)-1,2...)
Show SMILES CC(=O)N1Cc2cc(Br)ccc2N(Cc2cnc[nH]2)CC1Cc1ccccc1
Show InChI InChI=1S/C22H23BrN4O/c1-16(28)27-12-18-10-19(23)7-8-22(18)26(13-20-11-24-15-25-20)14-21(27)9-17-5-3-2-4-6-17/h2-8,10-11,15,21H,9,12-14H2,1H3,(H,24,25)
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PubMed
n/an/a 60n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of purified recombinant human farnesyltransferase (FT)

J Med Chem 43: 3587-95 (2000)


BindingDB Entry DOI: 10.7270/Q2WD3ZSV
More data for this
Ligand-Target Pair