BDBM50092426 CHEMBL421262::N-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-2,2-diphenyl-acetamide

SMILES: O=C(NCCC1CCN(CC2COc3ccccc3O2)CC1)C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=SAMSZIWMYYPCOJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092426   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50092426 (CHEMBL421262 | N-{2-[1-(2,3-Dihydro-benzo[1,4]diox...) Show SMILES O=C(NCCC1CCN(CC2COc3ccccc3O2)CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H34N2O3/c33-30(29(24-9-3-1-4-10-24)25-11-5-2-6-12-25)31-18-15-23-16-19-32(20-17-23)21-26-22-34-27-13-7-8-14-28(27)35-26/h1-14,23,26,29H,15-22H2,(H,31,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description In vitro inhibition of specific binding of [3H]-YM 09151-2 to Dopamine receptor D2 site in rat striatal tissue.				J Med Chem 43: 3653-64 (2000) BindingDB Entry DOI: 10.7270/Q2MW2GD3
					More data for this Ligand-Target Pair