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SMILES: Ic1ccc(cc1-c1cc(Cc2ccncc2)cc2cccnc12)N=[N+]=[N-]

InChI Key: InChIKey=RRZPTOSQHPPYDA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092627   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A


(Homo sapiens (Human))		BDBM50092627
PNG
(8-(5-Azido-2-iodo-phenyl)-6-pyridin-4-ylmethyl-qui...)
Show SMILES Ic1ccc(cc1-c1cc(Cc2ccncc2)cc2cccnc12)N=[N+]=[N-]
Show InChI InChI=1S/C21H14IN5/c22-20-4-3-17(26-27-23)13-18(20)19-12-15(10-14-5-8-24-9-6-14)11-16-2-1-7-25-21(16)19/h1-9,11-13H,10H2
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KEGG

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PC cid
PC sid
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Similars
PubMed
n/an/a 3.30n/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Inhibition of recombinant human PDE4A expressed in Sf9 cells

J Med Chem 43: 3820-3 (2000)


BindingDB Entry DOI: 10.7270/Q23T9GG9
More data for this
Ligand-Target Pair