BDBM50092660 4-Amino-benzamidine::4-aminobenzamidine::CHEMBL124632::CHEMBL545184::p-aminobenzamidine

SMILES: NC(=N)c1ccc(N)cc1

InChI Key: InChIKey=WPANETAWYGDRLL-UHFFFAOYSA-N

Data: 3 KI  1 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50092660   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trypsin-1 (Homo sapiens (Human))	BDBM50092660 (4-Amino-benzamidine | 4-aminobenzamidine | CHEMBL1...) Show SMILES NC(=N)c1ccc(N)cc1 Show InChI InChI=1S/C7H9N3/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H3,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant trypsin 1 using tosyl-GPR-pNA substrate by spectrophotometry				Bioorg Med Chem Lett 22: 4839-43 (2012) Article DOI: 10.1016/j.bmcl.2012.05.046 BindingDB Entry DOI: 10.7270/Q2QV3NKC
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50092660 (4-Amino-benzamidine | 4-aminobenzamidine | CHEMBL1...) Show SMILES NC(=N)c1ccc(N)cc1 Show InChI InChI=1S/C7H9N3/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H3,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometry				Bioorg Med Chem Lett 22: 4839-43 (2012) Article DOI: 10.1016/j.bmcl.2012.05.046 BindingDB Entry DOI: 10.7270/Q2QV3NKC
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50092660 (4-Amino-benzamidine | 4-aminobenzamidine | CHEMBL1...) Show SMILES NC(=N)c1ccc(N)cc1 Show InChI InChI=1S/C7H9N3/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H3,9,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	9.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human thrombin using tosyl-GPR-pNA substrate by spectrophotometry				Bioorg Med Chem Lett 22: 4839-43 (2012) Article DOI: 10.1016/j.bmcl.2012.05.046 BindingDB Entry DOI: 10.7270/Q2QV3NKC
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50092660 (4-Amino-benzamidine | 4-aminobenzamidine | CHEMBL1...) Show SMILES NC(=N)c1ccc(N)cc1 Show InChI InChI=1S/C7H9N3/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H3,9,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	7.80E+4	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to human alpha thrombin by Biocore A100 assay				Bioorg Med Chem Lett 22: 4839-43 (2012) Article DOI: 10.1016/j.bmcl.2012.05.046 BindingDB Entry DOI: 10.7270/Q2QV3NKC
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50092660 (4-Amino-benzamidine | 4-aminobenzamidine | CHEMBL1...) Show SMILES NC(=N)c1ccc(N)cc1 Show InChI InChI=1S/C7H9N3/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H3,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Urokinase-type plasminogen activator				J Med Chem 43: 3862-6 (2000) BindingDB Entry DOI: 10.7270/Q2VD6XQC
					More data for this Ligand-Target Pair