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SMILES: CN(CCC(=O)Nc1ccccc1Sc1ccc(Cl)cc1Cl)Cc1ccccc1

InChI Key: InChIKey=VNFICCZXOXJULI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092927   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1


(Homo sapiens (Human))		BDBM50092927
PNG
(3-(Benzyl-methyl-amino)-N-[2-(2,4-dichloro-phenyls...)
Show SMILES CN(CCC(=O)Nc1ccccc1Sc1ccc(Cl)cc1Cl)Cc1ccccc1
Show InChI InChI=1S/C23H22Cl2N2OS/c1-27(16-17-7-3-2-4-8-17)14-13-23(28)26-20-9-5-6-10-22(20)29-21-12-11-18(24)15-19(21)25/h2-12,15H,13-14,16H2,1H3,(H,26,28)
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PC cid
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Similars
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...

J Med Chem 43: 4025-40 (2000)


BindingDB Entry DOI: 10.7270/Q22Z14S7
More data for this
Ligand-Target Pair