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SMILES: OC(=O)\C=C\c1ccc(Sc2ccc(Cl)cc2Cl)c(Cl)c1

InChI Key: InChIKey=LQHOAIOYGSEKNV-QHHAFSJGSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092942   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1


(Homo sapiens (Human))		BDBM50092942
PNG
(3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl...)
Show SMILES OC(=O)\C=C\c1ccc(Sc2ccc(Cl)cc2Cl)c(Cl)c1
Show InChI InChI=1S/C15H9Cl3O2S/c16-10-3-5-14(12(18)8-10)21-13-4-1-9(7-11(13)17)2-6-15(19)20/h1-8H,(H,19,20)/b6-2+
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 2.60E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...

J Med Chem 43: 4025-40 (2000)


BindingDB Entry DOI: 10.7270/Q22Z14S7
More data for this
Ligand-Target Pair