BDBM50093552 CHEMBL3585735

SMILES: CCCn1c2cc(ccc2oc1=O)N1CC(=O)N(Cc2cc3cnc(nc3n2C)C(=O)N[C@@H](CCCCN)C#N)C1=O

InChI Key: InChIKey=AFHYYKVDKGPGHO-SFHVURJKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50093552   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen (Homo sapiens (Human))	BDBM50093552 (CHEMBL3585735) Show SMILES CCCn1c2cc(ccc2oc1=O)N1CC(=O)N(Cc2cc3cnc(nc3n2C)C(=O)N[C@@H](CCCCN)C#N)C1=O |r| Show InChI InChI=1S/C28H31N9O5/c1-3-10-35-21-12-19(7-8-22(21)42-28(35)41)36-16-23(38)37(27(36)40)15-20-11-17-14-31-24(33-25(17)34(20)2)26(39)32-18(13-30)6-4-5-9-29/h7-8,11-12,14,18H,3-6,9-10,15-16,29H2,1-2H3,(H,32,39)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Hiroshima International University Curated by ChEMBL					Assay Description Inhibition of urokinase (unknown origin) using Pyr-Gly-Arg-MCA as substrate by fluorescence analysis				Bioorg Med Chem 23: 3696-704 (2015) Article DOI: 10.1016/j.bmc.2015.04.013 BindingDB Entry DOI: 10.7270/Q2X92D2Q
					More data for this Ligand-Target Pair