BDBM50093628 6-[2-(4-Methoxy-phenyl)-ethyl]-2-methyl-4-piperidin-1-yl-5H-pyrrolo[3,2-d]pyrimidine::CHEMBL341993

SMILES: COc1ccc(CCc2cc3nc(C)nc(N4CCCCC4)c3[nH]2)cc1

InChI Key: InChIKey=QSJJVSIQQYSOHO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50093628   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50093628 (6-[2-(4-Methoxy-phenyl)-ethyl]-2-methyl-4-piperidi...) Show SMILES COc1ccc(CCc2cc3nc(C)nc(N4CCCCC4)c3[nH]2)cc1 Show InChI InChI=1S/C21H26N4O/c1-15-22-19-14-17(9-6-16-7-10-18(26-2)11-8-16)24-20(19)21(23-15)25-12-4-3-5-13-25/h7-8,10-11,14,24H,3-6,9,12-13H2,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assay				J Med Chem 43: 4288-312 (2000) BindingDB Entry DOI: 10.7270/Q2C828J1
					More data for this Ligand-Target Pair