BDBM50093930 2-(3,4-Difluoro-benzylsulfanyl)-1-furan-2-ylmethyl-5-pyrimidin-5-ylmethyl-1H-pyrimidin-4-one::CHEMBL313811

SMILES: Fc1ccc(CSc2nc(=O)c(Cc3cncnc3)cn2Cc2ccco2)cc1F

InChI Key: InChIKey=IAAVAYGIMHSAOH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50093930   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50093930 (2-(3,4-Difluoro-benzylsulfanyl)-1-furan-2-ylmethyl...) Show SMILES Fc1ccc(CSc2nc(=O)c(Cc3cncnc3)cn2Cc2ccco2)cc1F Show InChI InChI=1S/C21H16F2N4O2S/c22-18-4-3-14(7-19(18)23)12-30-21-26-20(28)16(6-15-8-24-13-25-9-15)10-27(21)11-17-2-1-5-29-17/h1-5,7-10,13H,6,11-12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	235	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of lipoprotein associated phospholipase A2 in human plasma				Bioorg Med Chem Lett 10: 2557-61 (2001) BindingDB Entry DOI: 10.7270/Q2B857C6
					More data for this Ligand-Target Pair