BDBM50093943 2-Benzylsulfanyl-1-(2-methoxy-ethyl)-5-pyrimidin-5-ylmethyl-1H-pyrimidin-4-one::CHEMBL87634

SMILES: COCCn1cc(Cc2cncnc2)c(=O)nc1SCc1ccccc1

InChI Key: InChIKey=FVCKIIMWPGLEFX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50093943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50093943 (2-Benzylsulfanyl-1-(2-methoxy-ethyl)-5-pyrimidin-5...) Show SMILES COCCn1cc(Cc2cncnc2)c(=O)nc1SCc1ccccc1 Show InChI InChI=1S/C19H20N4O2S/c1-25-8-7-23-12-17(9-16-10-20-14-21-11-16)18(24)22-19(23)26-13-15-5-3-2-4-6-15/h2-6,10-12,14H,7-9,13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of lipoprotein associated phospholipase A2 in human plasma				Bioorg Med Chem Lett 10: 2557-61 (2001) BindingDB Entry DOI: 10.7270/Q2B857C6
					More data for this Ligand-Target Pair