BDBM50093944 2-(4-Chloro-benzylsulfanyl)-1-furan-2-ylmethyl-5-pyrimidin-5-ylmethyl-1H-pyrimidin-4-one::CHEMBL83584

SMILES: Clc1ccc(CSc2nc(=O)c(Cc3cncnc3)cn2Cc2ccco2)cc1

InChI Key: InChIKey=PLBNCYNEMCLTND-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50093944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50093944 (2-(4-Chloro-benzylsulfanyl)-1-furan-2-ylmethyl-5-p...) Show SMILES Clc1ccc(CSc2nc(=O)c(Cc3cncnc3)cn2Cc2ccco2)cc1 Show InChI InChI=1S/C21H17ClN4O2S/c22-18-5-3-15(4-6-18)13-29-21-25-20(27)17(8-16-9-23-14-24-10-16)11-26(21)12-19-2-1-7-28-19/h1-7,9-11,14H,8,12-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of lipoprotein associated phospholipase A2 in human plasma				Bioorg Med Chem Lett 10: 2557-61 (2001) BindingDB Entry DOI: 10.7270/Q2B857C6
					More data for this Ligand-Target Pair