BDBM50093947 2-(4-Fluoro-benzylsulfanyl)-5-pyrimidin-5-ylmethyl-1-(2-thiophen-2-yl-ethyl)-1H-pyrimidin-4-one::CHEMBL313777

SMILES: Fc1ccc(CSc2nc(=O)c(Cc3cncnc3)cn2CCc2cccs2)cc1

InChI Key: InChIKey=ZWOYQNPKBLMNAO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50093947   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50093947 (2-(4-Fluoro-benzylsulfanyl)-5-pyrimidin-5-ylmethyl...) Show SMILES Fc1ccc(CSc2nc(=O)c(Cc3cncnc3)cn2CCc2cccs2)cc1 Show InChI InChI=1S/C22H19FN4OS2/c23-19-5-3-16(4-6-19)14-30-22-26-21(28)18(10-17-11-24-15-25-12-17)13-27(22)8-7-20-2-1-9-29-20/h1-6,9,11-13,15H,7-8,10,14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of lipoprotein associated phospholipase A2 in human plasma				Bioorg Med Chem Lett 10: 2557-61 (2001) BindingDB Entry DOI: 10.7270/Q2B857C6
					More data for this Ligand-Target Pair