Found 5 hits for monomerid = 50094494 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Catenin beta-1
(Homo sapiens (Human)) | BDBM50094494
(CHEMBL3589022)Show InChI InChI=1S/C12H7N5O3/c18-8(19)5-17-7-4-2-1-3-6(7)9-12(17)14-11-10(13-9)15-20-16-11/h1-4H,5H2,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description Inhibition of N-terminally His6-tagged human beta-catenin (residues 138-686)/C-terminally biotinylated human Tcf4 (residues 7-51) interaction after 4... |
J Med Chem 58: 4678-92 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00223 BindingDB Entry DOI: 10.7270/Q2G44S28 |
More data for this Ligand-Target Pair | |
Catenin beta-1
(Homo sapiens (Human)) | BDBM50094494
(CHEMBL3589022)Show InChI InChI=1S/C12H7N5O3/c18-8(19)5-17-7-4-2-1-3-6(7)9-12(17)14-11-10(13-9)15-20-16-11/h1-4H,5H2,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after... |
J Med Chem 58: 4678-92 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00223 BindingDB Entry DOI: 10.7270/Q2G44S28 |
More data for this Ligand-Target Pair | |
Catenin beta-1
(Homo sapiens (Human)) | BDBM50094494
(CHEMBL3589022)Show InChI InChI=1S/C12H7N5O3/c18-8(19)5-17-7-4-2-1-3-6(7)9-12(17)14-11-10(13-9)15-20-16-11/h1-4H,5H2,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein-labeled human APC-R3 (residues 1477-1519) interaction by FP co... |
J Med Chem 58: 4678-92 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00223 BindingDB Entry DOI: 10.7270/Q2G44S28 |
More data for this Ligand-Target Pair | |
Catenin beta-1
(Homo sapiens (Human)) | BDBM50094494
(CHEMBL3589022)Show InChI InChI=1S/C12H7N5O3/c18-8(19)5-17-7-4-2-1-3-6(7)9-12(17)14-11-10(13-9)15-20-16-11/h1-4H,5H2,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after... |
J Med Chem 58: 4678-92 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00223 BindingDB Entry DOI: 10.7270/Q2G44S28 |
More data for this Ligand-Target Pair | |
Catenin beta-1
(Homo sapiens (Human)) | BDBM50094494
(CHEMBL3589022)Show InChI InChI=1S/C12H7N5O3/c18-8(19)5-17-7-4-2-1-3-6(7)9-12(17)14-11-10(13-9)15-20-16-11/h1-4H,5H2,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein-labeled human E-cadherin (residues 819-873) interaction by FP ... |
J Med Chem 58: 4678-92 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00223 BindingDB Entry DOI: 10.7270/Q2G44S28 |
More data for this Ligand-Target Pair | |