BDBM50094677 3-(2-Dimethylamino-ethyl)-7-fluoro-1H-indol-4-ol::CHEMBL142368
SMILES: CN(C)CCc1c[nH]c2c(F)ccc(O)c12
InChI Key: InChIKey=LPDHCZRVHHMQEB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat)) | BDBM50094677 (3-(2-Dimethylamino-ethyl)-7-fluoro-1H-indol-4-ol |...) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2C receptor | J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50094677 (3-(2-Dimethylamino-ethyl)-7-fluoro-1H-indol-4-ol |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor | J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50094677 (3-(2-Dimethylamino-ethyl)-7-fluoro-1H-indol-4-ol |...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Evaluated for the binding constant at [3H]-8-OH-DPAT-labeled human 5-hydroxytryptamine 1A receptor receptor | J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50094677 (3-(2-Dimethylamino-ethyl)-7-fluoro-1H-indol-4-ol |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 4.92E+3 | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Evaluated for the effective concentration at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor | J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7 | |||||||||||
More data for this Ligand-Target Pair |