null

SMILES: N[C@]1(CC(O)[C@@H]2[C@H]1[C@@]2(F)C(O)=O)C(O)=O

InChI Key: InChIKey=IQUCMQGRKGYOJI-QEGHEOBESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50094845   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50094845 ((+/-)-2-Amino-6-fluoro-4-hydroxy-bicyclo[3.1.0]hex...) Show SMILES N[C@]1(CC(O)[C@@H]2[C@H]1[C@@]2(F)C(O)=O)C(O)=O Show InChI InChI=1S/C8H10FNO5/c9-8(6(14)15)3-2(11)1-7(10,4(3)8)5(12)13/h2-4,11H,1,10H2,(H,12,13)(H,14,15)/t2?,3-,4-,7+,8-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated in presence of 30 microM glutamic acid				J Med Chem 43: 4893-909 (2000) BindingDB Entry DOI: 10.7270/Q24J0DC8
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50094845 ((+/-)-2-Amino-6-fluoro-4-hydroxy-bicyclo[3.1.0]hex...) Show SMILES N[C@]1(CC(O)[C@@H]2[C@H]1[C@@]2(F)C(O)=O)C(O)=O Show InChI InChI=1S/C8H10FNO5/c9-8(6(14)15)3-2(11)1-7(10,4(3)8)5(12)13/h2-4,11H,1,10H2,(H,12,13)(H,14,15)/t2?,3-,4-,7+,8-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formation				J Med Chem 43: 4893-909 (2000) BindingDB Entry DOI: 10.7270/Q24J0DC8
					More data for this Ligand-Target Pair