null

SMILES: N[C@@]1([C@H]2[C@@H](CC1(F)F)[C@@H]2C(O)=O)C(O)=O

InChI Key: InChIKey=BYEDBNFXHDLGBU-NHDVCMSYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50094847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50094847 ((+/-)-2-Amino-3,3-difluoro-bicyclo[3.1.0]hexane-2,...) Show SMILES N[C@@]1([C@H]2[C@@H](CC1(F)F)[C@@H]2C(O)=O)C(O)=O Show InChI InChI=1S/C8H9F2NO4/c9-7(10)1-2-3(5(12)13)4(2)8(7,11)6(14)15/h2-4H,1,11H2,(H,12,13)(H,14,15)/t2-,3-,4-,8-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.62E+4	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated in presence of 30 microM glutamic acid				J Med Chem 43: 4893-909 (2000) BindingDB Entry DOI: 10.7270/Q24J0DC8
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50094847 ((+/-)-2-Amino-3,3-difluoro-bicyclo[3.1.0]hexane-2,...) Show SMILES N[C@@]1([C@H]2[C@@H](CC1(F)F)[C@@H]2C(O)=O)C(O)=O Show InChI InChI=1S/C8H9F2NO4/c9-7(10)1-2-3(5(12)13)4(2)8(7,11)6(14)15/h2-4H,1,11H2,(H,12,13)(H,14,15)/t2-,3-,4-,8-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formation				J Med Chem 43: 4893-909 (2000) BindingDB Entry DOI: 10.7270/Q24J0DC8
					More data for this Ligand-Target Pair