BDBM50094879 CHEMBL3589153

SMILES: COc1cc(ccc1N1C[C@H](O)[C@@H](O)C1)N1Cc2cn(nc2C1=O)-c1ccc(Cl)cc1

InChI Key: InChIKey=OGJOYPFWXIZCLU-OALUTQOASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50094879   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50094879 (CHEMBL3589153) Show SMILES COc1cc(ccc1N1C[C@H](O)[C@@H](O)C1)N1Cc2cn(nc2C1=O)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C22H21ClN4O4/c1-31-20-8-16(6-7-17(20)25-11-18(28)19(29)12-25)26-9-13-10-27(24-21(13)22(26)30)15-4-2-14(23)3-5-15/h2-8,10,18-19,28-29H,9,11-12H2,1H3/t18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in CHO cells by automated whole-cell patch clamp electrophysiology system				Bioorg Med Chem Lett 25: 2793-9 (2015) Article DOI: 10.1016/j.bmcl.2015.05.008 BindingDB Entry DOI: 10.7270/Q29C7053
					More data for this Ligand-Target Pair