BDBM50095274 (3-Bromo-phenyl)-(6-butoxy-quinazolin-4-yl)-amine::CHEMBL63450

SMILES: CCCCOc1ccc2ncnc(Nc3cccc(Br)c3)c2c1

InChI Key: InChIKey=UGBHNEOELUHXCF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50095274   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fructose-1,6-bisphosphatase 1 (FBPase) (Homo sapiens (Human))	BDBM50095274 ((3-Bromo-phenyl)-(6-butoxy-quinazolin-4-yl)-amine ...) Show SMILES CCCCOc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 Show InChI InChI=1S/C18H18BrN3O/c1-2-3-9-23-15-7-8-17-16(11-15)18(21-12-20-17)22-14-6-4-5-13(19)10-14/h4-8,10-12H,2-3,9H2,1H3,(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Concentration required to inhibit the human liver recombinant fructose-1,6-bisphosphatase.				Bioorg Med Chem Lett 11: 17-21 (2001) BindingDB Entry DOI: 10.7270/Q2HD7W52
					More data for this Ligand-Target Pair