Found 3 hits for monomerid = 50095395 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50095395
(3-[3-(4-Amino-phenyl)-ureido]-5-tert-butyl-thiophe...)Show InChI InChI=1S/C17H21N3O3S/c1-17(2,3)13-9-12(14(24-13)15(21)23-4)20-16(22)19-11-7-5-10(18)6-8-11/h5-9H,18H2,1-4H3,(H2,19,20,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center
Curated by ChEMBL
| Assay Description In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coli |
Bioorg Med Chem Lett 11: 9-12 (2001)
BindingDB Entry DOI: 10.7270/Q2JM28WH |
More data for this Ligand-Target Pair | |
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50095395
(3-[3-(4-Amino-phenyl)-ureido]-5-tert-butyl-thiophe...)Show InChI InChI=1S/C17H21N3O3S/c1-17(2,3)13-9-12(14(24-13)15(21)23-4)20-16(22)19-11-7-5-10(18)6-8-11/h5-9H,18H2,1-4H3,(H2,19,20,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of Raf1 kinase |
Bioorg Med Chem Lett 18: 2346-50 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.068 BindingDB Entry DOI: 10.7270/Q25X29S8 |
More data for this Ligand-Target Pair | |
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50095395
(3-[3-(4-Amino-phenyl)-ureido]-5-tert-butyl-thiophe...)Show InChI InChI=1S/C17H21N3O3S/c1-17(2,3)13-9-12(14(24-13)15(21)23-4)20-16(22)19-11-7-5-10(18)6-8-11/h5-9H,18H2,1-4H3,(H2,19,20,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center
Curated by ChEMBL
| Assay Description Inhibitory concentration against raf kinase. |
Bioorg Med Chem Lett 11: 2775-8 (2001)
BindingDB Entry DOI: 10.7270/Q2NS0VD5 |
More data for this Ligand-Target Pair | |