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SMILES: CNC(=O)c1[nH]c(cc1NC(=O)Nc1cccc(Cl)c1Cl)C(C)(C)C

InChI Key: InChIKey=GLDQOWDWBXXGMT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50095397   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50095397
PNG
(5-tert-Butyl-3-[3-(2,3-dichloro-phenyl)-ureido]-1H...)
Show SMILES CNC(=O)c1[nH]c(cc1NC(=O)Nc1cccc(Cl)c1Cl)C(C)(C)C
Show InChI InChI=1S/C17H20Cl2N4O2/c1-17(2,3)12-8-11(14(23-12)15(24)20-4)22-16(25)21-10-7-5-6-9(18)13(10)19/h5-8,23H,1-4H3,(H,20,24)(H2,21,22,25)
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PubMed
n/an/a 44n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coli

Bioorg Med Chem Lett 11: 9-12 (2001)


BindingDB Entry DOI: 10.7270/Q2JM28WH
More data for this
Ligand-Target Pair