BDBM50095401 5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carboxylic acid 3-hydroxy-propyl ester::CHEMBL18282

SMILES: Cc1ccc(NC(=O)Nc2cc(sc2C(=O)OCCCO)C(C)(C)C)cc1

InChI Key: InChIKey=AILXYVKRIDLPGA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50095401   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50095401 (5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...) Show SMILES Cc1ccc(NC(=O)Nc2cc(sc2C(=O)OCCCO)C(C)(C)C)cc1 Show InChI InChI=1S/C20H26N2O4S/c1-13-6-8-14(9-7-13)21-19(25)22-15-12-16(20(2,3)4)27-17(15)18(24)26-11-5-10-23/h6-9,12,23H,5,10-11H2,1-4H3,(H2,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of Mitogen-activated protein kinase p38 alpha 2				Bioorg Med Chem Lett 11: 9-12 (2001) BindingDB Entry DOI: 10.7270/Q2JM28WH
					More data for this Ligand-Target Pair