BDBM50095410 5-tert-Butyl-1-methyl-3-(3-phenyl-ureido)-1H-pyrrole-2-carboxylic acid methyl ester::CHEMBL279342

SMILES: COC(=O)c1c(NC(=O)Nc2ccccc2)cc(n1C)C(C)(C)C

InChI Key: InChIKey=RSXVPNKVQYUECM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50095410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50095410 (5-tert-Butyl-1-methyl-3-(3-phenyl-ureido)-1H-pyrro...) Show SMILES COC(=O)c1c(NC(=O)Nc2ccccc2)cc(n1C)C(C)(C)C Show InChI InChI=1S/C18H23N3O3/c1-18(2,3)14-11-13(15(21(14)4)16(22)24-5)20-17(23)19-12-9-7-6-8-10-12/h6-11H,1-5H3,(H2,19,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	947	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coli				Bioorg Med Chem Lett 11: 9-12 (2001) BindingDB Entry DOI: 10.7270/Q2JM28WH
					More data for this Ligand-Target Pair