BDBM50095414 5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carboxylic acid ethyl ester::CHEMBL275580

SMILES: CCOC(=O)c1sc(cc1NC(=O)Nc1ccc(C)cc1)C(C)(C)C

InChI Key: InChIKey=ZDXPIQOYIVXXTI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50095414 (5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...) Show SMILES CCOC(=O)c1sc(cc1NC(=O)Nc1ccc(C)cc1)C(C)(C)C Show InChI InChI=1S/C19H24N2O3S/c1-6-24-17(22)16-14(11-15(25-16)19(3,4)5)21-18(23)20-13-9-7-12(2)8-10-13/h7-11H,6H2,1-5H3,(H2,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibitory concentration against raf kinase.				Bioorg Med Chem Lett 11: 2775-8 (2001) BindingDB Entry DOI: 10.7270/Q2NS0VD5
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50095414 (5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...) Show SMILES CCOC(=O)c1sc(cc1NC(=O)Nc1ccc(C)cc1)C(C)(C)C Show InChI InChI=1S/C19H24N2O3S/c1-6-24-17(22)16-14(11-15(25-16)19(3,4)5)21-18(23)20-13-9-7-12(2)8-10-13/h7-11H,6H2,1-5H3,(H2,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of Mitogen-activated protein kinase p38 alpha 2				Bioorg Med Chem Lett 11: 9-12 (2001) BindingDB Entry DOI: 10.7270/Q2JM28WH
					More data for this Ligand-Target Pair