BDBM50095419 5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carboxylic acid 2-methoxy-ethyl ester::CHEMBL278646
SMILES: COCCOC(=O)c1sc(cc1NC(=O)Nc1ccc(C)cc1)C(C)(C)C
InChI Key: InChIKey=DKCJPCKZQBUQPV-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50095419 (5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 464 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center Curated by ChEMBL | Assay Description Inhibition of Mitogen-activated protein kinase p38 alpha 2 | Bioorg Med Chem Lett 11: 9-12 (2001) BindingDB Entry DOI: 10.7270/Q2JM28WH | |||||||||||
More data for this Ligand-Target Pair |