BDBM50095424 5-tert-Butyl-3-[3-(2-chloro-phenyl)-ureido]-1H-pyrrole-2-carboxylic acid methyl ester::CHEMBL18770

SMILES: COC(=O)c1[nH]c(cc1NC(=O)Nc1ccccc1Cl)C(C)(C)C

InChI Key: InChIKey=ZYAGTYJEVFJBND-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50095424   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50095424 (5-tert-Butyl-3-[3-(2-chloro-phenyl)-ureido]-1H-pyr...) Show SMILES COC(=O)c1[nH]c(cc1NC(=O)Nc1ccccc1Cl)C(C)(C)C Show InChI InChI=1S/C17H20ClN3O3/c1-17(2,3)13-9-12(14(21-13)15(22)24-4)20-16(23)19-11-8-6-5-7-10(11)18/h5-9,21H,1-4H3,(H2,19,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coli				Bioorg Med Chem Lett 11: 9-12 (2001) BindingDB Entry DOI: 10.7270/Q2JM28WH
					More data for this Ligand-Target Pair