BDBM50095483 3-Cyclohexylmethoxy-azetidine-1-carbonitrile::CHEMBL8726

SMILES: N#CN1CC(C1)OCC1CCCCC1

InChI Key: InChIKey=YQKMEJDAMLDEFV-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095483   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin B (Homo sapiens (Human))	BDBM50095483 (3-Cyclohexylmethoxy-azetidine-1-carbonitrile | CHE...) Show SMILES N#CN1CC(C1)OCC1CCCCC1 Show InChI InChI=1S/C11H18N2O/c12-9-13-6-11(7-13)14-8-10-4-2-1-3-5-10/h10-11H,1-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity tested against Human Cathepsin B using Z-Phe-Arg-pNA as substrate				J Med Chem 44: 94-104 (2001) BindingDB Entry DOI: 10.7270/Q2DV1J4R
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50095483 (3-Cyclohexylmethoxy-azetidine-1-carbonitrile | CHE...) Show SMILES N#CN1CC(C1)OCC1CCCCC1 Show InChI InChI=1S/C11H18N2O/c12-9-13-6-11(7-13)14-8-10-4-2-1-3-5-10/h10-11H,1-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity tested against Human Cathepsin K using Z-Phe-Arg-pNA as substrate				J Med Chem 44: 94-104 (2001) BindingDB Entry DOI: 10.7270/Q2DV1J4R
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50095483 (3-Cyclohexylmethoxy-azetidine-1-carbonitrile | CHE...) Show SMILES N#CN1CC(C1)OCC1CCCCC1 Show InChI InChI=1S/C11H18N2O/c12-9-13-6-11(7-13)14-8-10-4-2-1-3-5-10/h10-11H,1-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity tested against Human Cathepsin L using Z-Phe-Arg-pNA as substrate				J Med Chem 44: 94-104 (2001) BindingDB Entry DOI: 10.7270/Q2DV1J4R
					More data for this Ligand-Target Pair