BDBM50095499 Biphenyl-4-carboxylic acid (1-cyano-pyrrolidin-3-yl)-amide::CHEMBL8816

SMILES: O=C(NC1CCN(C1)C#N)c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=CCMLFCPHJPWXFB-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095499   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Procathepsin L (Homo sapiens (Human))	BDBM50095499 (Biphenyl-4-carboxylic acid (1-cyano-pyrrolidin-3-y...) Show SMILES O=C(NC1CCN(C1)C#N)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C18H17N3O/c19-13-21-11-10-17(12-21)20-18(22)16-8-6-15(7-9-16)14-4-2-1-3-5-14/h1-9,17H,10-12H2,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity tested against Human Cathepsin L using Z-Phe-Arg-pNA as substrate				J Med Chem 44: 94-104 (2001) BindingDB Entry DOI: 10.7270/Q2DV1J4R
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50095499 (Biphenyl-4-carboxylic acid (1-cyano-pyrrolidin-3-y...) Show SMILES O=C(NC1CCN(C1)C#N)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C18H17N3O/c19-13-21-11-10-17(12-21)20-18(22)16-8-6-15(7-9-16)14-4-2-1-3-5-14/h1-9,17H,10-12H2,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity tested against Human Cathepsin K using Z-Phe-Arg-pNA as substrate				J Med Chem 44: 94-104 (2001) BindingDB Entry DOI: 10.7270/Q2DV1J4R
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50095499 (Biphenyl-4-carboxylic acid (1-cyano-pyrrolidin-3-y...) Show SMILES O=C(NC1CCN(C1)C#N)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C18H17N3O/c19-13-21-11-10-17(12-21)20-18(22)16-8-6-15(7-9-16)14-4-2-1-3-5-14/h1-9,17H,10-12H2,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity tested against Human Cathepsin B using Z-Phe-Arg-pNA as substrate				J Med Chem 44: 94-104 (2001) BindingDB Entry DOI: 10.7270/Q2DV1J4R
					More data for this Ligand-Target Pair