null

SMILES: OC(=O)C(=O)CC(=O)c1ccsc1Cc1ccccc1

InChI Key: InChIKey=HTGWIZWPKBPISH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095511   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50095511 (4-(2-Benzyl-thiophen-3-yl)-2,4-dioxo-butyric acid ...) Show SMILES OC(=O)C(=O)CC(=O)c1ccsc1Cc1ccccc1 Show InChI InChI=1S/C15H12O4S/c16-12(9-13(17)15(18)19)11-6-7-20-14(11)8-10-4-2-1-3-5-10/h1-7H,8-9H2,(H,18,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description Strand transfer inhibitory activity against HIV-1 integrase				J Med Chem 48: 7084-8 (2005) Article DOI: 10.1021/jm050549e BindingDB Entry DOI: 10.7270/Q27W6BR1
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50095511 (4-(2-Benzyl-thiophen-3-yl)-2,4-dioxo-butyric acid ...) Show SMILES OC(=O)C(=O)CC(=O)c1ccsc1Cc1ccccc1 Show InChI InChI=1S/C15H12O4S/c16-12(9-13(17)15(18)19)11-6-7-20-14(11)8-10-4-2-1-3-5-10/h1-7H,8-9H2,(H,18,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of recombinant HIV-1 Integrase in strand transfer enzyme assay.				J Med Chem 43: 4923-6 (2001) BindingDB Entry DOI: 10.7270/Q2930SFS
					More data for this Ligand-Target Pair