null

SMILES: COCCOc1ccc(cc1)S(=O)(=O)N1C[C@H](C[C@@H]1C(=O)NO)n1c(O)cn(CC=C)c1=O

InChI Key: InChIKey=FUPNXXAGJGHNFI-WMLDXEAASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50095555   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50095555 (4-(3-Allyl-2,5-dioxo-imidazolidin-1-yl)-1-[4-(2-me...) Show SMILES COCCOc1ccc(cc1)S(=O)(=O)N1C[C@H](C[C@@H]1C(=O)NO)n1c(O)cn(CC=C)c1=O Show InChI InChI=1S/C20H26N4O8S/c1-3-8-22-13-18(25)24(20(22)27)14-11-17(19(26)21-28)23(12-14)33(29,30)16-6-4-15(5-7-16)32-10-9-31-2/h3-7,13-14,17,25,28H,1,8-12H2,2H3,(H,21,26)/t14-,17+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant matrix metalloproteinase-13 (collagenase-3)				J Med Chem 43: 4948-63 (2001) BindingDB Entry DOI: 10.7270/Q21N80DW
					More data for this Ligand-Target Pair
Matrilysin (Homo sapiens (Human))	BDBM50095555 (4-(3-Allyl-2,5-dioxo-imidazolidin-1-yl)-1-[4-(2-me...) Show SMILES COCCOc1ccc(cc1)S(=O)(=O)N1C[C@H](C[C@@H]1C(=O)NO)n1c(O)cn(CC=C)c1=O Show InChI InChI=1S/C20H26N4O8S/c1-3-8-22-13-18(25)24(20(22)27)14-11-17(19(26)21-28)23(12-14)33(29,30)16-6-4-15(5-7-16)32-10-9-31-2/h3-7,13-14,17,25,28H,1,8-12H2,2H3,(H,21,26)/t14-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloproteinase-7 (matrilysin, MMP-7)				J Med Chem 43: 4948-63 (2001) BindingDB Entry DOI: 10.7270/Q21N80DW
					More data for this Ligand-Target Pair
Matrilysin (Homo sapiens (Human))	BDBM50095555 (4-(3-Allyl-2,5-dioxo-imidazolidin-1-yl)-1-[4-(2-me...) Show SMILES COCCOc1ccc(cc1)S(=O)(=O)N1C[C@H](C[C@@H]1C(=O)NO)n1c(O)cn(CC=C)c1=O Show InChI InChI=1S/C20H26N4O8S/c1-3-8-22-13-18(25)24(20(22)27)14-11-17(19(26)21-28)23(12-14)33(29,30)16-6-4-15(5-7-16)32-10-9-31-2/h3-7,13-14,17,25,28H,1,8-12H2,2H3,(H,21,26)/t14-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP7				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50095555 (4-(3-Allyl-2,5-dioxo-imidazolidin-1-yl)-1-[4-(2-me...) Show SMILES COCCOc1ccc(cc1)S(=O)(=O)N1C[C@H](C[C@@H]1C(=O)NO)n1c(O)cn(CC=C)c1=O Show InChI InChI=1S/C20H26N4O8S/c1-3-8-22-13-18(25)24(20(22)27)14-11-17(19(26)21-28)23(12-14)33(29,30)16-6-4-15(5-7-16)32-10-9-31-2/h3-7,13-14,17,25,28H,1,8-12H2,2H3,(H,21,26)/t14-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloproteinase -2 (gelatinase-A)				J Med Chem 43: 4948-63 (2001) BindingDB Entry DOI: 10.7270/Q21N80DW
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50095555 (4-(3-Allyl-2,5-dioxo-imidazolidin-1-yl)-1-[4-(2-me...) Show SMILES COCCOc1ccc(cc1)S(=O)(=O)N1C[C@H](C[C@@H]1C(=O)NO)n1c(O)cn(CC=C)c1=O Show InChI InChI=1S/C20H26N4O8S/c1-3-8-22-13-18(25)24(20(22)27)14-11-17(19(26)21-28)23(12-14)33(29,30)16-6-4-15(5-7-16)32-10-9-31-2/h3-7,13-14,17,25,28H,1,8-12H2,2H3,(H,21,26)/t14-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloproteinase -3 (stromelysin)				J Med Chem 43: 4948-63 (2001) BindingDB Entry DOI: 10.7270/Q21N80DW
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50095555 (4-(3-Allyl-2,5-dioxo-imidazolidin-1-yl)-1-[4-(2-me...) Show SMILES COCCOc1ccc(cc1)S(=O)(=O)N1C[C@H](C[C@@H]1C(=O)NO)n1c(O)cn(CC=C)c1=O Show InChI InChI=1S/C20H26N4O8S/c1-3-8-22-13-18(25)24(20(22)27)14-11-17(19(26)21-28)23(12-14)33(29,30)16-6-4-15(5-7-16)32-10-9-31-2/h3-7,13-14,17,25,28H,1,8-12H2,2H3,(H,21,26)/t14-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloproteinase -1 (collagenase-1)				J Med Chem 43: 4948-63 (2001) BindingDB Entry DOI: 10.7270/Q21N80DW
					More data for this Ligand-Target Pair