BDBM50095618 CHEMBL341898::Indatraline::[3-(3,4-Dichloro-phenyl)-indan-1-yl]-methyl-amine;chloride

SMILES: CN[C@@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=SVFXPTLYMIXFRX-XJKSGUPXSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50095618   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50095618 (CHEMBL341898 | Indatraline | [3-(3,4-Dichloro-phen...) Show SMILES CN[C@@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H15Cl2N/c1-19-16-9-13(11-4-2-3-5-12(11)16)10-6-7-14(17)15(18)8-10/h2-8,13,16,19H,9H2,1H3/t13-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharm-Eco Laboratories Curated by ChEMBL					Assay Description Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporter				J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50095618 (CHEMBL341898 | Indatraline | [3-(3,4-Dichloro-phen...) Show SMILES CN[C@@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H15Cl2N/c1-19-16-9-13(11-4-2-3-5-12(11)16)10-6-7-14(17)15(18)8-10/h2-8,13,16,19H,9H2,1H3/t13-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharm-Eco Laboratories Curated by ChEMBL					Assay Description Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTI				J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50095618 (CHEMBL341898 | Indatraline | [3-(3,4-Dichloro-phen...) Show SMILES CN[C@@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H15Cl2N/c1-19-16-9-13(11-4-2-3-5-12(11)16)10-6-7-14(17)15(18)8-10/h2-8,13,16,19H,9H2,1H3/t13-,16+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharm-Eco Laboratories Curated by ChEMBL					Assay Description Inhibition of reuptake of [3H]-NE (20 nM) by norepinephrine transporter				J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50095618 (CHEMBL341898 | Indatraline | [3-(3,4-Dichloro-phen...) Show SMILES CN[C@@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H15Cl2N/c1-19-16-9-13(11-4-2-3-5-12(11)16)10-6-7-14(17)15(18)8-10/h2-8,13,16,19H,9H2,1H3/t13-,16+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharm-Eco Laboratories Curated by ChEMBL					Assay Description Binding affinity against norepinephrine cloned human transporter using 40-80 pM [125I]RTI				J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50095618 (CHEMBL341898 | Indatraline | [3-(3,4-Dichloro-phen...) Show SMILES CN[C@@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H15Cl2N/c1-19-16-9-13(11-4-2-3-5-12(11)16)10-6-7-14(17)15(18)8-10/h2-8,13,16,19H,9H2,1H3/t13-,16+/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharm-Eco Laboratories Curated by ChEMBL					Assay Description Inhibition of reuptake of [3H]DA (20 nM) by dopamine transporter				J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50095618 (CHEMBL341898 | Indatraline | [3-(3,4-Dichloro-phen...) Show SMILES CN[C@@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H15Cl2N/c1-19-16-9-13(11-4-2-3-5-12(11)16)10-6-7-14(17)15(18)8-10/h2-8,13,16,19H,9H2,1H3/t13-,16+/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharm-Eco Laboratories Curated by ChEMBL					Assay Description Binding affinity against Dopamine transporter using 40-80 pM [125I]RTI.				J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD
					More data for this Ligand-Target Pair