BDBM50095622 CHEMBL344116::[3-(3,4-Dichloro-phenyl)-indan-1-yl]-isopropyl-methyl-amine;chloride

SMILES: CCCN(C)[C@@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=NNNDXILSDZTFTR-QFBILLFUSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50095622   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50095622 (CHEMBL344116 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) Show SMILES CCCN(C)[C@@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H21Cl2N/c1-3-10-22(2)19-12-16(14-6-4-5-7-15(14)19)13-8-9-17(20)18(21)11-13/h4-9,11,16,19H,3,10,12H2,1-2H3/t16-,19+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharm-Eco Laboratories Curated by ChEMBL					Assay Description Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTI				J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50095622 (CHEMBL344116 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) Show SMILES CCCN(C)[C@@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H21Cl2N/c1-3-10-22(2)19-12-16(14-6-4-5-7-15(14)19)13-8-9-17(20)18(21)11-13/h4-9,11,16,19H,3,10,12H2,1-2H3/t16-,19+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharm-Eco Laboratories Curated by ChEMBL					Assay Description Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporter				J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50095622 (CHEMBL344116 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) Show SMILES CCCN(C)[C@@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H21Cl2N/c1-3-10-22(2)19-12-16(14-6-4-5-7-15(14)19)13-8-9-17(20)18(21)11-13/h4-9,11,16,19H,3,10,12H2,1-2H3/t16-,19+/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharm-Eco Laboratories Curated by ChEMBL					Assay Description Binding affinity against cloned human dopamine transporter using 40-80 pM [125I]RTI.				J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50095622 (CHEMBL344116 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) Show SMILES CCCN(C)[C@@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H21Cl2N/c1-3-10-22(2)19-12-16(14-6-4-5-7-15(14)19)13-8-9-17(20)18(21)11-13/h4-9,11,16,19H,3,10,12H2,1-2H3/t16-,19+/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharm-Eco Laboratories Curated by ChEMBL					Assay Description Inhibition of reuptake of [3H]DA (20 nM) by dopamine transporter				J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50095622 (CHEMBL344116 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) Show SMILES CCCN(C)[C@@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H21Cl2N/c1-3-10-22(2)19-12-16(14-6-4-5-7-15(14)19)13-8-9-17(20)18(21)11-13/h4-9,11,16,19H,3,10,12H2,1-2H3/t16-,19+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharm-Eco Laboratories Curated by ChEMBL					Assay Description Binding affinity against norepinephrine cloned human transporter using 40-80 pM [125I]RTI				J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50095622 (CHEMBL344116 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) Show SMILES CCCN(C)[C@@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H21Cl2N/c1-3-10-22(2)19-12-16(14-6-4-5-7-15(14)19)13-8-9-17(20)18(21)11-13/h4-9,11,16,19H,3,10,12H2,1-2H3/t16-,19+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharm-Eco Laboratories Curated by ChEMBL					Assay Description Inhibition of reuptake of [3H]-NE (20 nM) by norepinephrine transporter				J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD
					More data for this Ligand-Target Pair