BDBM50095816 2-{4-[4-(3-Bromo-phenyl)-piperazin-1-yl]-butyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL1204250::CHEMBL59791

SMILES: Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(Br)c1

InChI Key: InChIKey=SKLLLPUWHJHWAI-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50095816 (2-{4-[4-(3-Bromo-phenyl)-piperazin-1-yl]-butyl}-te...) Show SMILES Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(Br)c1 Show InChI InChI=1S/C21H29BrN4O2/c22-17-6-5-7-18(16-17)24-14-12-23(13-15-24)9-3-4-11-26-20(27)19-8-1-2-10-25(19)21(26)28/h5-7,16,27H,1-4,8-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor was determined using radioligand [3H]-8-OH-DPAT				J Med Chem 44: 186-97 (2001) BindingDB Entry DOI: 10.7270/Q2RN38MH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50095816 (2-{4-[4-(3-Bromo-phenyl)-piperazin-1-yl]-butyl}-te...) Show SMILES Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(Br)c1 Show InChI InChI=1S/C21H29BrN4O2/c22-17-6-5-7-18(16-17)24-14-12-23(13-15-24)9-3-4-11-26-20(27)19-8-1-2-10-25(19)21(26)28/h5-7,16,27H,1-4,8-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 44: 198-207 (2001) BindingDB Entry DOI: 10.7270/Q2MW2HWS
					More data for this Ligand-Target Pair