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SMILES: CCC[C@@H]1O[C@@H]2CC3C4C[C@H](F)C5=CC(=O)CC[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)SC(CCO)C(O)=O

InChI Key: InChIKey=IQBBFWUMZXRAND-HDTUZIMJSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096156   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50096156
PNG
(2-(4b,12-Difluoro-5-hydroxy-4a,6a-dimethyl-2-oxo-8...)
Show SMILES CCC[C@@H]1O[C@@H]2CC3C4C[C@H](F)C5=CC(=O)CC[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)SC(CCO)C(O)=O |t:12|
Show InChI InChI=1S/C27H38F2O7S/c1-4-5-22-35-21-12-15-16-11-18(28)17-10-14(31)6-8-24(17,2)26(16,29)20(32)13-25(15,3)27(21,36-22)37-19(7-9-30)23(33)34/h10,15-16,18-22,30,32H,4-9,11-13H2,1-3H3,(H,33,34)/t15?,16?,18-,19?,20-,21+,22+,24-,25-,26-,27-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

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DrugBank
antibodypedia
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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 400n/an/an/an/an/an/a



Glaxo Wellcome Research and Development

Curated by ChEMBL


Assay Description
Affinity for human glucocorticoid receptor

J Med Chem 44: 602-12 (2001)


BindingDB Entry DOI: 10.7270/Q2GM86JV
More data for this
Ligand-Target Pair