BDBM50096260 CHEMBL3593305
SMILES: Nc1ccccc1NC(=O)c1ccc(CNC(=O)\C=C\c2cnc3ccccn23)cc1
InChI Key: InChIKey=BEXLHXBJDKXXPK-OUKQBFOZSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50096260 (CHEMBL3593305) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 129 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Military Medical Sciences Curated by ChEMBL | Assay Description Inhibition of HDAC1 (unknown origin) preincubated for 5 mins followed by fluorogenic substrate addition measured after 30 mins by microplate reader a... | Eur J Med Chem 100: 270-6 (2015) Article DOI: 10.1016/j.ejmech.2015.05.045 BindingDB Entry DOI: 10.7270/Q2GT5PXH | |||||||||||
More data for this Ligand-Target Pair |