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SMILES: C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NC1COCC1=O

InChI Key: InChIKey=FPCFHFCNFSADMA-FTNKSUMCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096379   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cathepsin K


(Homo sapiens (Human))		BDBM50096379
PNG
(Benzo[b]thiophene-2-carboxylic acid [(S)-1-(4-oxo-...)
Show SMILES C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NC1COCC1=O
Show InChI InChI=1S/C16H16N2O4S/c1-9(15(20)18-11-7-22-8-12(11)19)17-16(21)14-6-10-4-2-3-5-13(10)23-14/h2-6,9,11H,7-8H2,1H3,(H,17,21)(H,18,20)/t9-,11?/m0/s1
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MMDB

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PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Smith Kline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human cysteine protease, cathepsin K.

Bioorg Med Chem Lett 11: 195-8 (2001)


BindingDB Entry DOI: 10.7270/Q2ZP45CQ
More data for this
Ligand-Target Pair