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SMILES: FC(F)(F)C12NC(=O)Nc3ccc(Cl)c(OC(=C1)C1CC1)c23

InChI Key: InChIKey=VQRZOKXWAYLSOE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096420   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50096420
PNG
(7-Chloro-5-cyclopropyl-3a-trifluoromethyl-3,3a-dih...)
Show SMILES FC(F)(F)C12NC(=O)Nc3ccc(Cl)c(OC(=C1)C1CC1)c23 |c:16|
Show InChI InChI=1S/C14H10ClF3N2O2/c15-7-3-4-8-10-11(7)22-9(6-1-2-6)5-13(10,14(16,17)18)20-12(21)19-8/h3-6H,1-2H2,(H2,19,20,21)
PDB
MMDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 90n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Tested for inhibitory concentration against HIV-1 non-nucleoside reverse transcriptase

Bioorg Med Chem Lett 11: 211-4 (2001)


BindingDB Entry DOI: 10.7270/Q2319WDF
More data for this
Ligand-Target Pair