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SMILES: [H][C@@]1(CCc2cc(F)c(F)cc12)[C@@H](N)CC(=O)N1Cc2nccnc2NC(=O)C1

InChI Key: InChIKey=IYILRUONGQGIJU-NHYWBVRUSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096869   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM50096869
PNG
(CHEMBL3580778)
Show SMILES [H][C@@]1(CCc2cc(F)c(F)cc12)[C@@H](N)CC(=O)N1Cc2nccnc2NC(=O)C1 |r|
Show InChI InChI=1S/C19H19F2N5O2/c20-13-5-10-1-2-11(12(10)6-14(13)21)15(22)7-18(28)26-8-16-19(24-4-3-23-16)25-17(27)9-26/h3-6,11,15H,1-2,7-9,22H2,(H,24,25,27)/t11-,15-/m0/s1
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Article
PubMed
n/an/a 90n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of DPP4 extracted from human Caco2 cells using H-Gly-Pro-AMC substrate after 10 mins by fluorescence assay

ACS Med Chem Lett 6: 602-6 (2015)


Article DOI: 10.1021/acsmedchemlett.5b00074
BindingDB Entry DOI: 10.7270/Q22J6DM2
More data for this
Ligand-Target Pair