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SMILES: [H][C@@]1(CCc2cc(F)c(F)cc12)[C@@H](N)CC(=O)N1Cc2ccccc2N(CC(=O)OCC)C(=O)C1

InChI Key: InChIKey=QGFUSLWPORKCNF-UWJYYQICSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096899   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM50096899
PNG
(CHEMBL3580792)
Show SMILES [H][C@@]1(CCc2cc(F)c(F)cc12)[C@@H](N)CC(=O)N1Cc2ccccc2N(CC(=O)OCC)C(=O)C1 |r|
Show InChI InChI=1S/C25H27F2N3O4/c1-2-34-25(33)14-30-22-6-4-3-5-16(22)12-29(13-24(30)32)23(31)11-21(28)17-8-7-15-9-19(26)20(27)10-18(15)17/h3-6,9-10,17,21H,2,7-8,11-14,28H2,1H3/t17-,21-/m0/s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.40n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of DPP4 extracted from human Caco2 cells using H-Gly-Pro-AMC substrate after 10 mins by fluorescence assay

ACS Med Chem Lett 6: 602-6 (2015)


Article DOI: 10.1021/acsmedchemlett.5b00074
BindingDB Entry DOI: 10.7270/Q22J6DM2
More data for this
Ligand-Target Pair