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BDBM50097025 4-Butyryl-piperazine-1-carboxylic acid 2-(3,5-dimethyl-phenyl)-3-{2-[4-(4-hydroxy-phenyl)-butylamino]-ethyl}-1H-indol-5-yl ester::CHEMBL148571

SMILES: CCCC(=O)N1CCN(CC1)C(=O)Oc1ccc2[nH]c(c(CCNCCCCc3ccc(O)cc3)c2c1)-c1cc(C)cc(C)c1

InChI Key: InChIKey=GUPYRLGNMXIKFF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097025   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)		BDBM50097025
PNG
(4-Butyryl-piperazine-1-carboxylic acid 2-(3,5-dime...)
Show SMILES CCCC(=O)N1CCN(CC1)C(=O)Oc1ccc2[nH]c(c(CCNCCCCc3ccc(O)cc3)c2c1)-c1cc(C)cc(C)c1
Show InChI InChI=1S/C37H46N4O4/c1-4-7-35(43)40-18-20-41(21-19-40)37(44)45-31-13-14-34-33(25-31)32(36(39-34)29-23-26(2)22-27(3)24-29)15-17-38-16-6-5-8-28-9-11-30(42)12-10-28/h9-14,22-25,38-39,42H,4-8,15-21H2,1-3H3
KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 30n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to rat Gonadotropin-releasing hormone receptor.

Bioorg Med Chem Lett 11: 515-7 (2001)


BindingDB Entry DOI: 10.7270/Q27080PS
More data for this
Ligand-Target Pair