BDBM50097235 (R)-N*1*-[(S)-2,2-Dimethyl-1-(1-methyl-1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-2-(3-phenyl-propyl)-succinamide::(R)-N1-((S)-3,3-dimethyl-1-oxo-1-(2-phenylpropan-2-ylamino)butan-2-yl)-N4-hydroxy-2-(3-phenylpropyl)succinamide::CHEMBL152855

SMILES: CC(C)(C)[C@H](NC(=O)[C@H](CCCc1ccccc1)CC(=O)NO)C(=O)NC(C)(C)c1ccccc1

InChI Key: InChIKey=XJTUBPYIIOWNPG-ZJSXRUAMSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097235   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stromelysin-1 (Homo sapiens (Human))	BDBM50097235 ((R)-N*1*-[(S)-2,2-Dimethyl-1-(1-methyl-1-phenyl-et...) Show SMILES CC(C)(C)[C@H](NC(=O)[C@H](CCCc1ccccc1)CC(=O)NO)C(=O)NC(C)(C)c1ccccc1 Show InChI InChI=1S/C28H39N3O4/c1-27(2,3)24(26(34)30-28(4,5)22-17-10-7-11-18-22)29-25(33)21(19-23(32)31-35)16-12-15-20-13-8-6-9-14-20/h6-11,13-14,17-18,21,24,35H,12,15-16,19H2,1-5H3,(H,29,33)(H,30,34)(H,31,32)/t21-,24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Ability to inhibit the matrix metalloprotease-3 by method of Knight et al using the fluorogenic peptide substrate.				Bioorg Med Chem Lett 11: 567-70 (2001) BindingDB Entry DOI: 10.7270/Q2610ZK1
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50097235 ((R)-N*1*-[(S)-2,2-Dimethyl-1-(1-methyl-1-phenyl-et...) Show SMILES CC(C)(C)[C@H](NC(=O)[C@H](CCCc1ccccc1)CC(=O)NO)C(=O)NC(C)(C)c1ccccc1 Show InChI InChI=1S/C28H39N3O4/c1-27(2,3)24(26(34)30-28(4,5)22-17-10-7-11-18-22)29-25(33)21(19-23(32)31-35)16-12-15-20-13-8-6-9-14-20/h6-11,13-14,17-18,21,24,35H,12,15-16,19H2,1-5H3,(H,29,33)(H,30,34)(H,31,32)/t21-,24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50097235 ((R)-N*1*-[(S)-2,2-Dimethyl-1-(1-methyl-1-phenyl-et...) Show SMILES CC(C)(C)[C@H](NC(=O)[C@H](CCCc1ccccc1)CC(=O)NO)C(=O)NC(C)(C)c1ccccc1 Show InChI InChI=1S/C28H39N3O4/c1-27(2,3)24(26(34)30-28(4,5)22-17-10-7-11-18-22)29-25(33)21(19-23(32)31-35)16-12-15-20-13-8-6-9-14-20/h6-11,13-14,17-18,21,24,35H,12,15-16,19H2,1-5H3,(H,29,33)(H,30,34)(H,31,32)/t21-,24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50097235 ((R)-N*1*-[(S)-2,2-Dimethyl-1-(1-methyl-1-phenyl-et...) Show SMILES CC(C)(C)[C@H](NC(=O)[C@H](CCCc1ccccc1)CC(=O)NO)C(=O)NC(C)(C)c1ccccc1 Show InChI InChI=1S/C28H39N3O4/c1-27(2,3)24(26(34)30-28(4,5)22-17-10-7-11-18-22)29-25(33)21(19-23(32)31-35)16-12-15-20-13-8-6-9-14-20/h6-11,13-14,17-18,21,24,35H,12,15-16,19H2,1-5H3,(H,29,33)(H,30,34)(H,31,32)/t21-,24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Ability to inhibit the matrix metalloprotease-2 by method of Knight et al using the fluorogenic peptide substrate.				Bioorg Med Chem Lett 11: 567-70 (2001) BindingDB Entry DOI: 10.7270/Q2610ZK1
					More data for this Ligand-Target Pair