null

SMILES: NS(=O)(=O)c1cc(c(NC(=O)CN(CCN(CCN(CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)cc1Cl)S(N)(=O)=O

InChI Key: InChIKey=AXIMANCGDYFPRM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50097278   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50097278 ((Carboxymethyl-{2-[carboxymethyl-(2-{carboxymethyl...) Show SMILES NS(=O)(=O)c1cc(c(NC(=O)CN(CCN(CCN(CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C20H29ClN6O13S2/c21-12-5-13(15(42(23,39)40)6-14(12)41(22,37)38)24-16(28)7-26(9-18(31)32)3-1-25(8-17(29)30)2-4-27(10-19(33)34)11-20(35)36/h5-6H,1-4,7-11H2,(H,24,28)(H,29,30)(H,31,32)(H,33,34)(H,35,36)(H2,22,37,38)(H2,23,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of cloned isozyme, human carbonic anhydrase II				Bioorg Med Chem Lett 11: 575-82 (2001) BindingDB Entry DOI: 10.7270/Q2KW5GJQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50097278 ((Carboxymethyl-{2-[carboxymethyl-(2-{carboxymethyl...) Show SMILES NS(=O)(=O)c1cc(c(NC(=O)CN(CCN(CCN(CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C20H29ClN6O13S2/c21-12-5-13(15(42(23,39)40)6-14(12)41(22,37)38)24-16(28)7-26(9-18(31)32)3-1-25(8-17(29)30)2-4-27(10-19(33)34)11-20(35)36/h5-6H,1-4,7-11H2,(H,24,28)(H,29,30)(H,31,32)(H,33,34)(H,35,36)(H2,22,37,38)(H2,23,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Human carbonic anhydrase II				J Med Chem 45: 1466-76 (2002) BindingDB Entry DOI: 10.7270/Q2N29XN9
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Bos taurus (bovine))	BDBM50097278 ((Carboxymethyl-{2-[carboxymethyl-(2-{carboxymethyl...) Show SMILES NS(=O)(=O)c1cc(c(NC(=O)CN(CCN(CCN(CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C20H29ClN6O13S2/c21-12-5-13(15(42(23,39)40)6-14(12)41(22,37)38)24-16(28)7-26(9-18(31)32)3-1-25(8-17(29)30)2-4-27(10-19(33)34)11-20(35)36/h5-6H,1-4,7-11H2,(H,24,28)(H,29,30)(H,31,32)(H,33,34)(H,35,36)(H2,22,37,38)(H2,23,39,40)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against bovine carbonic anhydrase IV				J Med Chem 45: 1466-76 (2002) BindingDB Entry DOI: 10.7270/Q2N29XN9
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50097278 ((Carboxymethyl-{2-[carboxymethyl-(2-{carboxymethyl...) Show SMILES NS(=O)(=O)c1cc(c(NC(=O)CN(CCN(CCN(CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C20H29ClN6O13S2/c21-12-5-13(15(42(23,39)40)6-14(12)41(22,37)38)24-16(28)7-26(9-18(31)32)3-1-25(8-17(29)30)2-4-27(10-19(33)34)11-20(35)36/h5-6H,1-4,7-11H2,(H,24,28)(H,29,30)(H,31,32)(H,33,34)(H,35,36)(H2,22,37,38)(H2,23,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of cloned isozyme, human carbonic anhydrase IV				Bioorg Med Chem Lett 11: 575-82 (2001) BindingDB Entry DOI: 10.7270/Q2KW5GJQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50097278 ((Carboxymethyl-{2-[carboxymethyl-(2-{carboxymethyl...) Show SMILES NS(=O)(=O)c1cc(c(NC(=O)CN(CCN(CCN(CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C20H29ClN6O13S2/c21-12-5-13(15(42(23,39)40)6-14(12)41(22,37)38)24-16(28)7-26(9-18(31)32)3-1-25(8-17(29)30)2-4-27(10-19(33)34)11-20(35)36/h5-6H,1-4,7-11H2,(H,24,28)(H,29,30)(H,31,32)(H,33,34)(H,35,36)(H2,22,37,38)(H2,23,39,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Human carbonic anhydrase I				J Med Chem 45: 1466-76 (2002) BindingDB Entry DOI: 10.7270/Q2N29XN9
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50097278 ((Carboxymethyl-{2-[carboxymethyl-(2-{carboxymethyl...) Show SMILES NS(=O)(=O)c1cc(c(NC(=O)CN(CCN(CCN(CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C20H29ClN6O13S2/c21-12-5-13(15(42(23,39)40)6-14(12)41(22,37)38)24-16(28)7-26(9-18(31)32)3-1-25(8-17(29)30)2-4-27(10-19(33)34)11-20(35)36/h5-6H,1-4,7-11H2,(H,24,28)(H,29,30)(H,31,32)(H,33,34)(H,35,36)(H2,22,37,38)(H2,23,39,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibition of cloned isozyme, human carbonic anhydrase I				Bioorg Med Chem Lett 11: 575-82 (2001) BindingDB Entry DOI: 10.7270/Q2KW5GJQ
					More data for this Ligand-Target Pair