BDBM50097327 CHEMBL345715::Phosphoric acid 12-(2-{1-[2-(5-chloro-indol-1-yl)-ethyl]-1H-indol-3-yl}-acetylamino)-dodecyl ester cyclohexyl ester; compound with triethyl-amine
SMILES: OP(=O)(OCCCCCCCCCCCCNC(=O)Cc1cn(CCn2ccc3cc(Cl)ccc23)c2ccccc12)OC1CCCCC1
InChI Key: InChIKey=QFBPBSCKTKUNKD-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50097327 (CHEMBL345715 | Phosphoric acid 12-(2-{1-[2-(5-chlo...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.01E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University Curated by ChEMBL | Assay Description Inhibition of human geranylgeranyltransferase-I | Bioorg Med Chem Lett 11: 583-5 (2001) BindingDB Entry DOI: 10.7270/Q2XK8DV2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50097327 (CHEMBL345715 | Phosphoric acid 12-(2-{1-[2-(5-chlo...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University Curated by ChEMBL | Assay Description Inhibitory concentration against human telomerase | Bioorg Med Chem Lett 11: 583-5 (2001) BindingDB Entry DOI: 10.7270/Q2XK8DV2 | |||||||||||
More data for this Ligand-Target Pair |