BDBM50097330 CHEMBL346776::Phosphoric acid 3-chloro-phenyl ester 2-cyano-ethyl ester 12-(2-{1-[3-(3-methyl-indol-1-yl)-propyl]-1H-indol-3-yl}-acetylamino)-dodecyl ester

SMILES: Cc1cn(CCCn2cc(CC(=O)NCCCCCCCCCCCCOP(=O)(OCCC#N)Oc3cccc(Cl)c3)c3ccccc23)c2ccccc12

InChI Key: InChIKey=WCCLMKBUGVTUPN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097330   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50097330 (CHEMBL346776 | Phosphoric acid 3-chloro-phenyl est...) Show SMILES Cc1cn(CCCn2cc(CC(=O)NCCCCCCCCCCCCOP(=O)(OCCC#N)Oc3cccc(Cl)c3)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C43H54ClN4O5P/c1-35-33-47(41-23-12-10-21-39(35)41)27-18-28-48-34-36(40-22-11-13-24-42(40)48)31-43(49)46-26-14-8-6-4-2-3-5-7-9-15-29-51-54(50,52-30-17-25-45)53-38-20-16-19-37(44)32-38/h10-13,16,19-24,32-34H,2-9,14-15,17-18,26-31H2,1H3,(H,46,49)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibitory concentration against human telomerase				Bioorg Med Chem Lett 11: 583-5 (2001) BindingDB Entry DOI: 10.7270/Q2XK8DV2
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