BDBM50097488 CHEMBL3585869

SMILES: OC(CO\N=C\c1ccc(OC(F)F)c(OC2CCCC2)c1)CN1CCOCC1

InChI Key: InChIKey=HOXHVATUHQBKTK-FSJBWODESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097488   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50097488 (CHEMBL3585869) Show SMILES OC(CO\N=C\c1ccc(OC(F)F)c(OC2CCCC2)c1)CN1CCOCC1 Show InChI InChI=1S/C20H28F2N2O5/c21-20(22)29-18-6-5-15(11-19(18)28-17-3-1-2-4-17)12-23-27-14-16(25)13-24-7-9-26-10-8-24/h5-6,11-12,16-17,20,25H,1-4,7-10,13-14H2/b23-12+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D3 expressed in baculoviral system using cAMP as substrate by fluorescence polarization assay				Bioorg Med Chem 23: 3426-35 (2015) Article DOI: 10.1016/j.bmc.2015.04.027 BindingDB Entry DOI: 10.7270/Q2NC62ZZ
					More data for this Ligand-Target Pair