BDBM50097604 3-(4-Methoxy-phenyl)-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-pyridine::CHEMBL160447

SMILES: COc1ccc(cc1)-c1cncc(OC[C@@H]2CCCN2C)c1

InChI Key: InChIKey=QWPKKGKNBWKYGZ-INIZCTEOSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50097604 (3-(4-Methoxy-phenyl)-5-((S)-1-methyl-pyrrolidin-2-...) Show SMILES COc1ccc(cc1)-c1cncc(OC[C@@H]2CCCN2C)c1 Show InChI InChI=1S/C18H22N2O2/c1-20-9-3-4-16(20)13-22-18-10-15(11-19-12-18)14-5-7-17(21-2)8-6-14/h5-8,10-12,16H,3-4,9,13H2,1-2H3/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-(-)-cytisine binding to whole rat brain membranes at Nicotinic acetylcholine receptor alpha4-beta2				Bioorg Med Chem Lett 11: 631-3 (2001) BindingDB Entry DOI: 10.7270/Q2WM1CPS
					More data for this Ligand-Target Pair