BDBM50097611 5-[5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridin-3-yl]-pyrimidine::CHEMBL160321

SMILES: CN1CCC[C@H]1COc1cncc(c1)-c1cncnc1

InChI Key: InChIKey=KZSSEEXJLWVALH-AWEZNQCLSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50097611 (5-[5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridin...) Show SMILES CN1CCC[C@H]1COc1cncc(c1)-c1cncnc1 Show InChI InChI=1S/C15H18N4O/c1-19-4-2-3-14(19)10-20-15-5-12(6-16-9-15)13-7-17-11-18-8-13/h5-9,11,14H,2-4,10H2,1H3/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-(-)-cytisine binding to whole rat brain membranes at Nicotinic acetylcholine receptor alpha4-beta2				Bioorg Med Chem Lett 11: 631-3 (2001) BindingDB Entry DOI: 10.7270/Q2WM1CPS
					More data for this Ligand-Target Pair