BDBM50097616 3-(2,4-Dichloro-phenyl)-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-pyridine::CHEMBL157250

SMILES: CN1CCC[C@H]1COc1cncc(c1)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=WAQCQCZXLRJXOS-AWEZNQCLSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097616   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50097616 (3-(2,4-Dichloro-phenyl)-5-((S)-1-methyl-pyrrolidin...) Show SMILES CN1CCC[C@H]1COc1cncc(c1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C17H18Cl2N2O/c1-21-6-2-3-14(21)11-22-15-7-12(9-20-10-15)16-5-4-13(18)8-17(16)19/h4-5,7-10,14H,2-3,6,11H2,1H3/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-(-)-cytisine binding to whole rat brain membranes at Nicotinic acetylcholine receptor alpha4-beta2				Bioorg Med Chem Lett 11: 631-3 (2001) BindingDB Entry DOI: 10.7270/Q2WM1CPS
					More data for this Ligand-Target Pair