null

SMILES: O=C(NCCC#N)c1ccc(NCc2cncn2Cc2ccc(cc2)C#N)cc1-c1ccccc1

InChI Key: InChIKey=QCIVONWRSKAXKG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50097813   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Mus musculus)	BDBM50097813 (5-{[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-ami...) Show SMILES O=C(NCCC#N)c1ccc(NCc2cncn2Cc2ccc(cc2)C#N)cc1-c1ccccc1 Show InChI InChI=1S/C28H24N6O/c29-13-4-14-32-28(35)26-12-11-24(15-27(26)23-5-2-1-3-6-23)33-18-25-17-31-20-34(25)19-22-9-7-21(16-30)8-10-22/h1-3,5-12,15,17,20,33H,4,14,18-19H2,(H,32,35)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of mammalian H-Ras processing in NIH 3T3 cells				Bioorg Med Chem Lett 11: 761-4 (2001) BindingDB Entry DOI: 10.7270/Q26W99CH
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50097813 (5-{[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-ami...) Show SMILES O=C(NCCC#N)c1ccc(NCc2cncn2Cc2ccc(cc2)C#N)cc1-c1ccccc1 Show InChI InChI=1S/C28H24N6O/c29-13-4-14-32-28(35)26-12-11-24(15-27(26)23-5-2-1-3-6-23)33-18-25-17-31-20-34(25)19-22-9-7-21(16-30)8-10-22/h1-3,5-12,15,17,20,33H,4,14,18-19H2,(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of mammalian Farnesyltransferase				Bioorg Med Chem Lett 11: 761-4 (2001) BindingDB Entry DOI: 10.7270/Q26W99CH
					More data for this Ligand-Target Pair