BDBM50097891 4-Fluoro-5-methoxy-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole::CHEMBL352186

SMILES: COc1ccc2[nH]cc(CCN3CCCC3)c2c1F

InChI Key: InChIKey=FJCRAYWNOXUYOO-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097891   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50097891 (4-Fluoro-5-methoxy-3-(2-pyrrolidin-1-yl-ethyl)-1H-...) Show SMILES COc1ccc2[nH]cc(CCN3CCCC3)c2c1F Show InChI InChI=1S/C15H19FN2O/c1-19-13-5-4-12-14(15(13)16)11(10-17-12)6-9-18-7-2-3-8-18/h4-5,10,17H,2-3,6-9H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinitty towards human 5-hydroxytryptamine 1A receptor was determined using [3H]-8-OH-DPAT-as radioligand				Bioorg Med Chem Lett 11: 793-5 (2001) BindingDB Entry DOI: 10.7270/Q2ZC824R
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50097891 (4-Fluoro-5-methoxy-3-(2-pyrrolidin-1-yl-ethyl)-1H-...) Show SMILES COc1ccc2[nH]cc(CCN3CCCC3)c2c1F Show InChI InChI=1S/C15H19FN2O/c1-19-13-5-4-12-14(15(13)16)11(10-17-12)6-9-18-7-2-3-8-18/h4-5,10,17H,2-3,6-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinitty towards rat 5-hydroxytryptamine 2A receptor was determined using [125I]- DOI as radioligand				Bioorg Med Chem Lett 11: 793-5 (2001) BindingDB Entry DOI: 10.7270/Q2ZC824R
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50097891 (4-Fluoro-5-methoxy-3-(2-pyrrolidin-1-yl-ethyl)-1H-...) Show SMILES COc1ccc2[nH]cc(CCN3CCCC3)c2c1F Show InChI InChI=1S/C15H19FN2O/c1-19-13-5-4-12-14(15(13)16)11(10-17-12)6-9-18-7-2-3-8-18/h4-5,10,17H,2-3,6-9H2,1H3	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinitty towards rat 5-hydroxytryptamine 2C receptor was determined using [125I]- DOI as radioligand				Bioorg Med Chem Lett 11: 793-5 (2001) BindingDB Entry DOI: 10.7270/Q2ZC824R
					More data for this Ligand-Target Pair