null

SMILES: Fc1ccc(cc1)C(CCN1CCC2(CC1)OCCc1ccccc21)C(=O)NCc1cc(F)cc(c1)C(F)(F)F

InChI Key: InChIKey=PPJHFLILDOHJMC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50097893   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Mus musculus)	BDBM50097893 (CHEMBL3589847) Show SMILES Fc1ccc(cc1)C(CCN1CCC2(CC1)OCCc1ccccc21)C(=O)NCc1cc(F)cc(c1)C(F)(F)F Show InChI InChI=1S/C31H31F5N2O2/c32-25-7-5-22(6-8-25)27(29(39)37-20-21-17-24(31(34,35)36)19-26(33)18-21)9-13-38-14-11-30(12-15-38)28-4-2-1-3-23(28)10-16-40-30/h1-8,17-19,27H,9-16,20H2,(H,37,39)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Westf£lische Wilhelms-Universit£t M£nster Curated by ChEMBL					Assay Description Antagonist activity against mouse CCR2B expressed in human U2OS cells co-expressing beta-arrestin assessed as inhibition of mouse CCL2-induced beta-a...				Bioorg Med Chem 23: 4034-49 (2015) Article DOI: 10.1016/j.bmc.2015.02.019 BindingDB Entry DOI: 10.7270/Q23F4RD1
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50097893 (CHEMBL3589847) Show SMILES Fc1ccc(cc1)C(CCN1CCC2(CC1)OCCc1ccccc21)C(=O)NCc1cc(F)cc(c1)C(F)(F)F Show InChI InChI=1S/C31H31F5N2O2/c32-25-7-5-22(6-8-25)27(29(39)37-20-21-17-24(31(34,35)36)19-26(33)18-21)9-13-38-14-11-30(12-15-38)28-4-2-1-3-23(28)10-16-40-30/h1-8,17-19,27H,9-16,20H2,(H,37,39)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
Westf£lische Wilhelms-Universit£t M£nster Curated by ChEMBL					Assay Description Antagonist activity against human CCR2B expressed in Chem-1 cells assessed as inhibition of human CCL2-induced intracellular calcium flux incubated f...				Bioorg Med Chem 23: 4034-49 (2015) Article DOI: 10.1016/j.bmc.2015.02.019 BindingDB Entry DOI: 10.7270/Q23F4RD1
					More data for this Ligand-Target Pair